Xue Laboratory of Biooganic Chemistry Department of Chemistry University of the Pacific |
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Research |
Selected Publications
Referred Publications: Xue, L.; Charles, I.; Arya, D. P. Pyrene-neomycin conjugate: dual recognition of a DNA triple helix. Chem. Commun. 2002, 1, 70-71. Charles, I.; Xue, L.; Arya, D. P. Synthesis of aminoglycoside-DNA conjugates. Bioorg. Med. Chem. Lett. 2002, 12, 1259-1262. Arya, D. P.; Micovic, L.; Charles, I.; Coffee, Jr. R. L.; Willis, B.; Xue, L. Neomycin binding to Watson-Hoogsteen (W-H) triplex groove: a model. J. Am. Chem. Soc. 2003, 125, 3733-3744. Arya, D. P.; Xue, L.; Tennant, P. Combining the best in triplex recognition: synthesis and nucleic acid binding of a BQQ-neomycin conjugate. J. Am. Chem. Soc. 2003, 125, 8070-8071. Arya, D. P.; Xue, L.; Willis, B. Aminoglycoside (neomycin) preference is for A-form nucleic acids, not just RNA: results from a competition dialysis study. J. Am. Chem. Soc. 2003, 125, 10148-10149. Arya, D. P.; Coffee, Jr. R. L.; Xue, L. From triplex to B-form duplex stabilization: reversal of target selectivity by aminoglycoside dimers. Bioorg. Med. Chem. Lett. 2004, 14, 4643-4646. Xue, L.; Greenberg, M. M. Use of fluorescent sensors to determine that 2-deoxyribonolactone is the major alkali-labile deoxyribose lesion produced in oxidatively damaged DNA. Angew. Chem. Intl. Ed., 2007, 46, 561-564. Xue, L.; Greenberg, M. M. Facile quantification of lesions derived from 2’-deoxyguanosine in DNA. J. Am. Chem. Soc. 2007, 129, 7010-7011. Patents: Arya, D. P.; Xue, L.; Bert, W.; Charles, I. Compositions and methods using aminoglycosides to bind DNA and RNA. US60/709,263. 2005. |
Department of Chemistry, University of the Pacific 3601 Pacific Avenue, Stockton, CA 95211 |
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