Patrick R. Jones

Ph.D (1971), Stanford University, with Professor Henry Taube                       
B.S. (1966), University of Texas, Austin
B.A. (1966), University of Texas, Austin, Phi Beta Kappa

Physical Chemistry, Mass Spectrometry

Classroom Building Room118
Phone: (209) 946-2442
Fax: (209) 946-2607
email: pjones@pacific.edu

Research Topics
Atmospheric pressure ionization mass spectrometry; physical processes of photochemistry; low energy electron-excitation of adsorbed gases; development of metabolite analysis methods using mass spectrometry; oxygen atom chemistry; physical and biological aspects of organometallic complexes; Fourier transform ion cyclotron resonance mass spectrometry; mass spectrometry of biological compounds; applications of Accelerator Mass Spectrometry to biological systems.
    COLLABORATIONS with    O. D. Sparkman        J. Ren        A. Franz

Representative Publications

O. David Sparkman, Patrick R. Jones, and Matthew Curtis, “Accurate Mass Measurements with a Reflectron Time-of-Flight Mass Spectrometer and the Direct Analysis in Real Time (DART) Interface for the Identification of Unknown Compounds Below Masses of 500 Da,” in Liquid Chromatography Time-of-Flight Mass Spectrometry, eds. Imma Ferrer, and E. Michael Thurman, John Wiley and Sons, 2009, pp. 229 – 245.

O. David Sparkman, Patrick R. Jones, and Matthew Curtis, “Anatomy of an Ion’s Fragmentation After Electron Ionization, Part II, Current Trends in Mass Spectrometry, July 2009, pp 12 – 19.

O. David Sparkman, Patrick R. Jones, and Matthew Curtis, “Anatomy of an Ion’s Fragmentation After Electron Ionization, Part I, Current Trends in Mass Spectrometry, May 2009, pp 18 – 29.

KeshavVasanthavada, Xiaoyi Hu, Arnold M. Falick, Coby La Mattina, Anne M. F. Moore, Patrick R. Jones, Russell Yee, Ryan Reza, Tiffany Tuton, Craig Vierra, Aciniform Spidroin, a Constituent of Egg Case Sacs and Wrapping Silk Fibers from the Black Widow Spider Lactrodectus Hesperus, Journal of Biological Chemistry (2007) 282(48) 35088 - 35097.

Teresa M. Vail, O. David Sparkman, Patrick R. Jones, Rapid and Unambiguous identification of Melamine in Contaminated Pet Food Based on Mass Spectrometry with Four Degrees of Confirmation,  Journal of Analytical Toxicology, 2007, 31, 304-312.

 Lorena Rios, Charles Moore, Patrick R. Jones, Persistent Organic Pollutants Carried by Synthetic Polymers in the Ocean Environment. Marine Pollution Bulletin, 2007, 54, 1230 – 1237. doi:10:1016/j.marpolbul.2007.03.022.

 Xiaoyi Hu, Kristin Kohler, Arnold M. Falick, Anne M. F. Moore, Patrick R. Jones, and Craig Vierra, Spider Egg Case Core Fibers:  Trimeric Complexes Assembled from TuSp1, ECP-1, and ECP-2.  Biochemistry 2006, 45, 3506 – 3516.

 Smita S. Matkar, Lisa A. Wrischnik, Patrick R. Jones, Utha Hellmann-Blumberg, Two closely related nickel complexes have different effects on DNA damage and cell viability, Biochemical and Biophysical Research Communications 343 (2006) 754 – 761.

 Zhang, Kangling; Tang, Jennifer; Jones, Patrick R..  Qualitative and quantitative analysis of histone acetylation by mass spectrometry.    Current Pharmaceutical Analysis (2005), 1(3),  319-328. 

Hu, Xiaoyi; Lawrence, Barbara; Kohler, Kristin; Falick, Arnold M.; Moore, Anne M. F.; McMullen, Erin; Jones, Patrick R.; Vierra, Craig.  Araneoid Egg Case Silk: A Fibroin with Novel Ensemble Repeat Units from the Black Widow Spider, Latrodectus hesperus.    Biochemistry (2005), 44(30),  10020-10027. 

Hu, Xiaoyi; Kohler, Kristin; Falick, Arnold M.; Moore, Anne M. F.; Jones, Patrick R.; Sparkman, O. David; Vierra, Craig.  Egg Case Protein-1: a new class of silk proteins with fibroin-like properties from the spider Latrodectus hesperus.    Journal of Biological Chemistry (2005),  280(22),  21220-21230.

Kangling Zhang, Katherine E. Williams, Lan Huang, Peter Yau, Joseph S. Siino, E. Morton Bradbury, Patrick R. Jones, Michael J. Minch, and Alma L. Burlingame, “Identification of Acetylation and Methylation Sites of HeLa Histone H4 by Mass Spectrometry” Molecular and Cellular Proteomics, 1 (2002) 500 – 508.
 

Kangling Zhang, Hui Tang, Patrick R. Jones, Fan Xiang, Peter M. Yau, and Alma L. Burlingame, “Identification of Acetylation and Methylation Sites of Histone H3 from Chicken Erythrocytes by High Accuracy Matrix Assisted Laser Desorption Ionization – Time of Flight MALDI-PSD, and Nanospray Ionization Tandem Mass Spectrometry,” Analytical Biochemistry, 306 (2002) 259-269.

Dipali Nimbalkar, Raj Birudaraj, Patrick R. Jones and Timothy J. Smith, “Activation of diacetyldapsone and a preliminary evaluation of a cyclodextrin-diacetyldapsone complex in cultured lung cells,” Biotechnol. Appl. Biochem. 33 (2001) 123-125.

Recent Presentations

Matthew E. Curtis, Patrick R. Jones and O.D. Sparkman, University of the Pacific, USA
"Capturing Radical Species Formed in the Helium Metastable Beam Produced from the Direct Analysis in Real Time Ion Source" International Mass Spectrometry Conference, Bremmen, Germany, September 2009.

O. David Sparkman; Matthew Curtis; Monika Kaur; Jianhua Ren; Patrick R. Jones, “Fragmentation of Isomers of 4-keto C10H20O as a Means of Understanding EI Behavior for Purposes of Structural Elucidation of Unknowns,” Proceedings of the 57^th Conference ot the American Society for Mass Spectrometry and Allied Topics, Philadelphia, PA, June 2009.

Chang-nan Chen, Jentai Shiea, Yi-Feng Lin, Patrick R. Jones, “The development of Quantitative Real-Time Detection of Flavors During Fermentation by Fused-Droplet Electrospray ionization (FD-ESI) Mass Spectrometry,” Proceedings of the 56^th Conference ot the American Society for Mass Spectrometry and Allied Topics, Denver, Colorado, June 2008.

O. David Sparkman, Patrick R. Jones, Matthew Curtis, Teresa Vail, “Methods of Quantitative Measurements Using a Helium Metastable-Beam Open-Air Ion Source Mass Spectrometer,” Proceedings of the 56^th Conference ot the American Society for Mass Spectrometry and Allied Topics, Denver, Colorado, June 2008.

Lorena M. Rios, Patrick R. Jones, O. David Sparkman, and Charles Moore, “Endocrine Disrupters Adsorbed on Macro and Micro Plastic Debris in the Ocean,” Proceedings of the 56^th Conference ot the American Society for Mass Spectrometry and Allied Topics, Denver, Colorado, June 2008.

Matthew Curtis, O. David Sparkman and Patrick R. Jones, “Utility of Reactions in the Source of a Helium Metastable-Beam Open-Air Ion Source Mass Spectrometer,” Proceedings of the 56^th Conference ot the American Society for Mass Spectrometry and Allied Topics, Denver, Colorado, June 2008.

Presentations (full list)